Date: 9/30/2009
TUMS PR: Two cases of childhood Systemic lupus erythematosus (SLE) with recurrent pulmonary hemorrhage who were unresposive to high-dose corticosteroid, cytotoxic therapy, IVIG, etc responded successfully to mycophenolate mofetil. [H]
Based on a report by the public relations of TUMS Children Medical Center, Dr. Mohammad Hassan Moradinejad has published an article in the journal of "Rheumatoly International", volume 29, 2009 about two cases of childhood Systemic lupus erythematosus (SLE) with recurrent pulmonary hemorrhage.
SLE is a chronic autoimmune disease of unknown etiology with multisystem involvement. A number of pulmonary complications including pleuritis, pneumonitis, infectious pneumonia, and pulmonary hemorrhage have been reported in patients with SLE. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with SLE.
In this report, two cases of childhood SLE with recurrent pulmonary hemorrhage, who were unresponsive to treatment with high-dose corticosteroids, cytotoxic therapy, IVIG or plasmaphoresis, responded to intravenous mycophenolate mofetil, an immunosuppressive agent used in solid organ transplantation. A multimodal therapy including mycophenolate mofetil was successfully used in the two children.
http://publicrelations.tums.ac.ir/english/news/detail.asp?newsID=13671
No comments:
Post a Comment